Morphofunctional characteristics of the mucous membrane of the masticatory apparatus in experimental carcinogenesis

BACKGROUND: Diseases of the gastrointestinal tract are often accompanied by changes in oral cavity. This is largely due to morphological and functional unity mucosa entire digestive tract. Therefore, role a dentist important early oncological alertness for detecting malignant neoplasms at an stage their development.
 AIM: Present results study mucous membrane mouth animal during experimental carcinogenesis.
 MATERIAL AND METHODS: The was carried out on 168 sexually mature outbred white male rats kept under standard vivarium conditions. animals were divided into following groups: control 84 individuals with simulated colon adenocarcinomatosis. Every 30 days experiment, 12 withdrawn from groups. Carcinogenesis modeled introduction 1,2-dimethylhydrazine dihydrochloride, previously diluted isotonic sodium chloride solution. Using histological study, studied both examined groups.
 RESULTS: dynamics revealed against background development adenocarcinomatosis large intestine; destructive-degenerative sclerotic intestine, severity which increased accordance period neoplasm, established.
 CONCLUSION: intestine mouth, caused chemical carcinogen, indicate high risk developing tumor spread all parts